Great Britain Proteins from Sciatic - Nerve Myelin in Quaking and Jimpy Mice By JEAN - MARIE MATTHIEU

a severe myelin deficit secondary to an arrest of myelinogenesis. A great number of morphological and biochemical studies have shown that the myelin sheath formed in the brain of Quaking mutants is abnormal (for a review, see Hogan, 1977). Although the central nervous system of the Quaking mice was studied extensively, only a little attention was devoted to myelin in the peripheral nervous system. Although less affected than central nervous system, peripheral